Here are some interesting notes about Chain of Fools which have appeared in various trivia questions on Internet boards:

1. Chain of Fools was directed by a team of Swedish directors and is credited to Traktor,the registered corporate name of the group. Could the real directors be The Shiny New Enemies.
2. Craig Ferguson, who plays the slimy, incredibly stupid Melander Stevens is a well known Scottish comedian and comic actor, who has appeared in several films, including a zany flick about an International Hair Dresser's contest, Blow Dry. He is most familiar to American audiences as Drew Cary's TV boss.
3. Salma Hayek is the only actor to appear in three films with Elijah Wood—The Faculty, Chain of Fools and Spy Kids 3D.
4. Tom Wilkinson stars with Elijah Wood in a very different role in Eternal Sunshine of the Spotless Mind. Mr. Wilkinson, famous for his roles on the BBC, especially in Martin Chuzzlewit, won an Academy Award for In the Bedroom and is currently playing a flat accented American crime boss in the smash hit Batman Begins.
5. The three Senator Dove assassination sequences show a host of subtle differences (the third, of course being the revelation of Mikey's distorting of truth). These portrayals, by Elijah Wood, match his three different audiences—Bollingsworth (the client), Kresk and Bollingsworth (the comatose).
6. Orlando Jones pointed portrayal of Miss Cocoa, the drag queen is outrageously funny, although all too short. (S)he must be attracted to bad guys as (s)he kept house with Avnet and winds up with Kerner.
7. Chain of Fools is filled with subtle hysteria. This reviewers favorite is Paulie's inability to spell and his compulsion to practice his letters in old fashion grammar school forms. He struggles to write in the boxes. The note he leaves regarding Scottie's kidnapping is delicious.
8. Scottie, the child actor in the piece, is a raging scamp. In many ways, he takes a page from Elijah Wood's early roles, where he's energetic, a rip from hell and very intelligent. When he says, "you want my poop?" one can hear Elijah as an echo from North—"Why would you show my crack?"
9. Jeff Goldblum's Avnet does as much sight gagging as line delivery. He slips, he chokes, he plays dead, he staggers and falls out a window.
10. Suicide is one of the main links in this Chain of Fools. The funny part about it, it has no bearing on any theme or relevance to the plot. Everyone is either contemplating suicide or the child of suicidal parents. It bonds them together. But it's like saying they are all related because they wear shoes. It's just one of those things in this delicious comedy that makes one say Wait a minute. Did he say suicide again? Where are we going with this. Its as quirky as, let's say, a Pastrami on Rye at a crime scene with a bungling old fart who shows up saying "I'm here to heist away."
11. The film is rated R. Elijah Wood since The Faculty has been gravitating to R rated films. Although he only uses the F word once in Chain of Fools, unlike Ash Wednesday where he uses it 13 times (but whose counting), he does say Shit once but not scatologically.
12. Elijah Wood only uses a Gun in three films—Chain of Fools, Ash Wednesday and All I Want/Try Seventeen.
13. Chain of Fools had a limited release. In this same year (2000), Elijah Wood made another filmThe Bumblebee Flies Anyway, also limited release. Since then, he's become a limited release leader with Green Street Hooligans and Everything Is Illuminated, both 2005. He also kept lower acting profiles in three other films Black & White (1999), Eternal Sunshine of the Spotless Mind (2004) and Sin City (2005). It's a good thing he's a household name allowing him the luxury of being his own oarsman following in the footsteps of great Indy actors like Kevin Bacon and Johnny Depp.